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KMID : 0665220200330030317
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Korean Journal of Food and Nutrition
2020 Volume.33 No. 3 p.317 ~ p.321
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Effect of Pumpkin Sweet Potato (Ipomoea batas L.) Water Extracts on Mouse Spleen and Cytokine Cell Activation
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Ryu Hye-Sook
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Abstract
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Pumpkin sweet potato (Ipomoea batas L.) has been known as a traditional remedy and food source, not only in South Korea but worldwide. It is rich in fiber, potassium, vitamin C, and other minerals and vitamins, making it a nutritional food loved by many. showed that pumpkin sweet potato had antioxidant biological effects. The in vitro study showed that both splenocytes and cytokine production byactivated peritoneal macrophages increased when water extracts were supplemented at 100 and 250 μL/mL. Notably, the production of IL-1β, TNF-α, and IFN-γ by splenocytes was significantly increased at 100 μL/mL. The results suggest that supplementation with pumpkin sweet potato (Ipomoea batas L.) water extract may enhance immune function by stimulating splenocyte proliferation and improving cytokine production, activating macrophages in vitro.
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KEYWORD
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splenocytes proliferation, pumpkin sweet potato, cytokine production
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